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Bayesian networks can be used to model gene regulatory networks because of its capability of capturing causal relationships between genes. However, learning Bayesian network is an NP-hard problem. Hill climbing methods are used in BN learning, in which K2 is a frequently used greedy search algorithm. But the performance of K2 algorithm is greatly affected by a prior ordering of input nodes and relatively...
Bayesian network is a knowledge representation formalism that has been proven to be valuable in gene regulatory network reconstruction. However, it is showed that the structure learning of Bayesian networks is an NP-hard problem. Several heuristic searching techniques have been used to find better network structures. Among these algorithms, K2 algorithm has been found to be the most successful. However,...
Microarray technology enables the study of measuring gene expression levels for thousands of genes simultaneously. Cluster analysis of gene expression profiles has been applied for analyzing the function of gene because co-expressed genes are likely to share the same biological function. K-MEANS is one of well-known clustering methods. However, it requires a precise estimation of number of clusters...
This paper presents a novel genetic particle-pair optimizer (GPPO) for vector quantization of image coding. GPPO only applies a particle-pair that consists of two particles, which contributes to the relief of huge computation load in most existing vector quantization algorithms. GPPO combines the advantage both in genetic algorithms and particle swarm optimization, due to the use of genetic operators...
Matrix factorization plays an important role in scientific computation. The widely used one is singular value decomposition (SVD) which approximates the original data matrix with three lower rank matrices with orthogonality constraints. Recently nonnegative matrix factorization (NMF) considering the nonnegativity of data makes the results more interpretable than those of SVD. However NMF finds only...
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