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Autofluorescence imaging has shown high sensitivity for early diagnosis and detection of cancer in humans. However, it has a limitation diagnostic specificity due to high false positive rates. In our study, we develop an integrated fluorescence endoscopic imaging and point spectroscopy system for real-time tissue measurements. The results show that endoscope-based autofluorescene spectroscopy and...
We develop an NIR autofluorescence imaging system combination with polarization technique to explore its potential for cancer diagnosis and detection. Colon tissues (normal vs. cancer) from patients who underwent colonoscopy or surgical resections were used for this study. The tissue imaging including NIR white light images, autofluorescence (AF) images and FPI images (parallel-, and perpendicular-...
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