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The present study was performed to identify antidepressant-like activity of icariin in prenatally stressed male rats.The effects of icariin on PRS-induced depression were examined using sucrose preference test (SPT) and forced swimming test (FST) in male offspring, and measuring protein and mRNA expressions of group I mGluRs receptors and EAAT2 via western blotting and quantitative real-time PCR assays...
To clarify the alterations of proliferation and differentiation of hippocampal cells in prenatally stressed rats.We investigated the impact of prenatal restraint stress on the hipocampal cell proliferation in the progeny with 5-bromo-2′-deoxyuridine (BrdU), which is a marker of proliferating cells and their progeny. In addition, we observed the differentiation of neural stem cells (NSCs) with double...
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