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Heart failure with reduced ejection fraction (HFrEF) exhibits a “reverse metabolic profile”. Whether this profile exists in HF with preserved ejection fraction (HFpEF) is unknown. We tested the hypothesis that HFpEF and HFrEF are similar regarding concentrations of and prognostic impact of leptin and adiponectin.In patients with HFpEF(n=79), HFrEF(n=84), and controls(n=71), we analyzed serum leptin...
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