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DOI: 10.1002/pmic.201800136
In article number 1800136, Yu et al. analyze the adrenal gland lipid droplet (LD) proteomes from human, macaque monkey, and rodent and reveal that steroidogenic enzymes are also present in abundance on LDs. The enzymes found include 3β‐hydroxysteroid dehydrogenase (HSD3B) and estradiol 17β‐dehydrogenase 11 (HSD17B11). Furthermore, the analyses demonstrate that HSD3B2 is...
Steroid hormones play essential roles for living organisms. It has been long and well established that the endoplasmic reticulum (ER) and mitochondria are essential sites for steroid hormone biosynthesis because several steroidogenic enzymes are located in these organelles. The adrenal gland lipid droplet (LD) proteomes from human, macaque monkey, and rodent are analyzed, revealing that steroidogenic...
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