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Objective
Excess visceral adipose tissue (VAT) is a major risk factor for metabolic syndrome (MetS) and clinical guidelines have been proposed to define VAT levels associated with increased risk. The aim was to standardize VAT measures between two dual‐energy x‐ray absorptiometry (DXA) manufacturers who provide different VAT estimates to support standardization of measures across imaging modalities...
Objective
The study aimed to identify BMI‐related lipids and to explore the role of lipids linking BMI and gestational diabetes mellitus (GDM).
Methods
Plasma lipidome, height, and weight were measured in early pregnancy among 1008 women. Pearson correlation analyses and least absolute shrinkage and selection operator regression (LASSO) were performed to identify BMI‐associated lipids. Based on...
Objective
Receptor‐interacting serine/threonine‐protein kinase 1 (RIP1) is a well‐documented key regulator of TNFα‐mediated inflammation, apoptosis, and necroptosis, which contribute to the development of obesity‐related metabolic diseases such as nonalcoholic steatohepatitis. However, the mechanism regarding how RIP1 influences obesity‐related insulin resistance remains elusive.
Methods
Primary...