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Epidemiologic studies of PM2.5 (particulate matter with aerodynamic diameter ≤2.5 μm) and black carbon (BC) typically use ambient measurements as exposure proxies given that individual measurement is infeasible among large populations. Failure to account for variation in exposure will bias epidemiologic study results. The ability of ambient measurement as a proxy of exposure in regions with heavy...
The underlying mechanisms about the association between ambient fine particulate matter (PM2.5) and lung function were unclear. Few epidemiological studies have evaluated the potential mediating effects of serum club cell secretory protein (Clara) (CC16), a biomarker of pulmonary epithelium integrity.To evaluate the short-term effect of personal PM2.5 exposure on lung function and to explore the potential...
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