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The binding of [ 3 H]angiotensin II to AT 1 receptors on Chinese Hamster Ovary cells expressing the human AT 1 receptor (CHO-AT 1 cells) is potently inhibited by venoms of the marine snails Conus geographus and C. betulinus. On the other hand, the binding of the nonpeptide AT 1 receptor-selective antagonist [ 3 H]candesartan is not affected but competition...
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