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The developing embryo is very sensitive to oxidative stress and excess reactive oxygen species (ROS) generation is often associated with cardiovascular malformation. However, little is known about the adverse effects of ROS during heart morphogenesis, especially during the formation of the atria and ventricles.We have treated early chick embryos with 2,2-azobis (2-amidinopropane) dihydrochloride (AAPH)...
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