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The discovery of exosomes, which are small, 30–100 nm sized extracellular vesicles that are released by virtual all cells, has initiated a rapidly expanding and vibrant research field. Current investigations are mainly directed toward the role of exosomes in intercellular communication and their potential value as biomarkers for a broad set of diseases. By horizontal transfer of molecular information...
Background InformationExosomes are small RNA‐ and protein‐containing extracellular vesicles (EVs) that are thought to mediate hetero‐ and homotypic intercellular communication between normal and malignant cells. Tumour‐derived exosomes are believed to promote re‐programming of the tumour‐associated stroma to favour tumour growth and metastasis. Currently, exosomes have been intensively studied in...
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