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Background The use of mechanical bowel preparation is much debated. Methods We evaluated the effects of polyethylene glycol (PEG), with or without a single dose of 3.0 mmol butyrate (BUT), on the bursting pressure (BP) of an intact colon segment and a colon anastomosis in rats. Also, histopathologic damage was studied. Results In rats without colectomy, the mean BP was 159.2 mmHg (SD=18.9)...
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