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Studies have shown emerging evidence that rupture of coronary plaque containing a lipid-rich core with subsequent thrombus formation is the most frequent mechanism by which atherosclerosis leads to the acute ischaemic syndromes of unstable angina, acute myocardial infarction, and often times, sudden cardiac death. However, since the lumen is not significantly blocked in these cases, such “vulnerable”...
During the last decade, close resemblance between the zebrafish heart and human heart physiology has been discovered [1] andzebrafish (Danio rerio) has become an emerging animal model for studying side effects developmental drugs may impose on the heart [2][3]. More interestingly, contrary to human heart the zebrafish heart has a remarkable ability to “regenerate” after severe injury [4], making it...
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