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Following acute myocardial infarction (AMI), the acute inflammatory response contributes to wound healing but also to progressive myocardial injury. Interleukin-21 (IL-21) plays a key role in immunoregulation; whether IL-21 is associated with left ventricular (LV) remodelling after AMI is unknown.Plasma IL-21 concentrations were measured in 100 patients (age 58.9±12.0years, 77% male) admitted with...
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