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Ultrasensitive identification of biomarkers in biofluids is essential for the precise diagnosis of diseases. For the gold standard approaches, polymerase chain reaction and enzyme‐linked immunosorbent assay, cumbersome operational steps hinder their point‐of‐care applications. Here, a bionic biomarker entrapment system (BioES) is implemented, which employs a multi‐body Y‐shaped tetrahedral DNA probe...
Nanocatalysts are promising tumor therapeutics due to their ability to induce reactive oxygen species in the tumor microenvironment. Although increasing metal loading can improve catalytic activity, the quandary of high metal content versus potential systemic biotoxicity remains challenging. Here, a fully exposed active site strategy by site‐specific anchoring of single iridium (Ir) atoms on the outer...
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