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Analysis of the chemical‐organic knowledge represented as a giant network reveals that it contains millions of reaction sequences closing into cycles. Without realizing it, independent chemists working at different times have jointly created examples of cyclic sequences that allow for the recovery of useful reagents and for the autoamplification of synthetically important molecules, those that mimic...
Seit der Einführung des ersten dokumentierten Forschungsprojekts (Dendral, 1965) zur rechnergestützten organischen Synthese ist ein halbes Jahrhundert vergangen. In den 1970er und 1980er Jahren wurden viele weitere Programme entwickelt, doch bis zu den 2000er Jahren war der Enthusiasmus dieser Pionierzeit weitgehend verschwunden, und wegen der schwierigen Aufgabe, die Planung organischer Synthesen...
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