Wyniki wyszukiwania dla: Hua Chen

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artykuł

Reduction of Oxidative Stress and Excitotoxicity by Mesenchymal Stem Cell Biomimetic Co‐Delivery System for Cerebral Ischemia‐Reperfusion Injury Treatment

Qi Zhang, Shengnan Li, Hua Chen, Jiaqing Yin, więcej

Small > 20 > 43 > n/a - n/a

A cerebral ischemia‐reperfusion injury is ensued by an intricate interplay between various pathological processes including excitotoxicity, oxidative stress, inflammation, and apoptosis. For a long time, drug intervention policies targeting a single signaling pathway have failed to achieve the anticipated clinical efficacy in the intricate and dynamic inflammatory environment of the brain. Moreover,...

artykuł

Systematic synthesis and identification of monolignol pathway metabolites

Chung‐Ting Kao, Fan‐Wei Yang, Meng‐Chen Wu, Tzu‐Huan Hung, więcej

New Phytologist > 244 > 4 > 1143 - 1167

Monolignol serves as the building blocks to constitute lignin, the second abundant polymer on Earth. Despite two decades of diligent efforts, complete identification of all metabolites in the currently proposed monolignol biosynthesis pathway has proven elusive. This limitation also hampers their potential application. One of the primary obstacles is the challenge of assembling a collection of all...

artykuł

Association between parental well‐being and preschooler stress measured as hair cortisol concentration: A prospective cohort study

Yun‐Shiang Kang, Ling‐Chu Chien, Jian‐Pei Huang, Yen‐Tzu Fan, więcej

Stress and Health > 40 > 5 > n/a - n/a

Hair cortisol concentration (HCC) is a valuable biomarker for evaluating chronic stress in preschoolers. However, few studies have explored early life HCC and its associated factors. This prospective cohort study analysed the HCC in children aged 6–48 months and its associations with parental HCC as well as positive and negative parental mental health outcomes. We used data from the ongoing Longitudinal...

artykuł

3D Fractal Dimension Analysis: Prognostic Value of Right Ventricular Trabecular Complexity in Participants with Arrhythmogenic Cardiomyopathy

Jin‐Yu Zheng, Bing‐Hua Chen, Rui Wu, Dong‐Aolei An, więcej

Journal of Magnetic Resonance Imaging > 60 > 5 > 1964 - 1973

Background Arrhythmogenic cardiomyopathy (ACM) is characterized by progressive myocardial fibro‐fatty infiltration accompanied by trabecular disarray. Traditionally, two‐dimensional (2D) instead of 3D fractal dimension (FD) analysis has been used to evaluate trabecular disarray. However, the prognostic value of trabecular disorder assessed by 3D FD measurement remains unclear. Purpose To investigate...

artykuł

Association of sodium‐glucose cotransporter 2 inhibitors with risk of incident dementia and all‐cause mortality in older patients with type 2 diabetes: A retrospective cohort study using the TriNetX US collaborative networks

Yen‐Wei Pai, I‐Chieh Chen, Jun‐Fu Lin, Xiao‐Hui Chen, więcej

Diabetes, Obesity and Metabolism > 26 > 11 > 5420 - 5430

Background Limited evidence exists to support any specific medication over others to prevent dementia in older patients with type 2 diabetes (T2D). We investigated whether treatment with sodium‐glucose cotransporter 2 (SGLT‐2) inhibitors is associated with a lower risk of incident dementia and all‐cause mortality, relative to dipeptidyl peptidase‐4 (DPP‐4) inhibitors and glucagon‐like peptide‐1 receptor...

artykuł

Front Cover: Tuning Tumor Targeting and Ratiometric Photoacoustic Imaging by Fine‐Tuning Torsion Angle for Colorectal Liver Metastasis Diagnosis (Chem. Eur. J. 55/2024)

Jinyuan Xu, Zhangkang Lv, Liping Wang, Xingqing Wu, więcej

Chemistry – A European Journal > 30 > 55 > n/a - n/a

The Front Cover depicts a convertible cyanine/hemicyanine photoacoustic (PA) dye platform Cy‐HCy with optimized NIR ratiometric PA properties and tunable tumor‐targeting capabilities for PA probe development and precise diagnosis of colorectal cancer liver metastasis. More information can be found in the Research Article by X.‐C. Shen, H. Chen, and co‐workers (DOI: 10.1002/chem.202402019).

artykuł

Tuning Tumor Targeting and Ratiometric Photoacoustic Imaging by Fine‐Tuning Torsion Angle for Colorectal Liver Metastasis Diagnosis

Jinyuan Xu, Zhangkang Lv, Liping Wang, Xingqing Wu, więcej

Chemistry – A European Journal > 30 > 55 > n/a - n/a

Photoacoustic (PA) tomography is an emerging biomedical imaging technology for precision cancer medicine. Conventional small‐molecule PA probes usually exhibit a single PA signal and poor tumor targeting that lack the imaging reliability. Here, we introduce a series of cyanine/hemicyanine interconversion dyes (denoted Cy‐HCy) for PA/fluorescent dual‐mode probe development that features optimized ratiometric...

artykuł

Controllable Interface Engineering for the Preparation of High Rate Silicon Anode

Lei Wang, Ji‐Jun Lu, Shao‐Yuan Li, Feng‐Shuo Xi, więcej

Advanced Functional Materials > 34 > 40 > n/a - n/a

Silicon (Si) is considered to be the promising candidate anode for the next generation of high‐energy‐density batteries. However, the poor initial coulombic efficiency (ICE) and rate performance severely hinder its commercial development. Here, fully exploits the 2D structure of photovoltaic silicon waste (PV‐WSi), combining with the advantage of controllable depositing layers offered by fluidized...

artykuł

Unveiling the Twisted Aromatic Donor Effect on the Nonlinear Response of D‐π‐A Type Malononitrile‐Derived Chromophores

Xiang‐Zhao Zhu, Song‐Hua Chen, Jia‐Bei Xu, Jian‐hua Huang, więcej

Chemistry – A European Journal > 30 > 53 > n/a - n/a

This study presents the design, synthesis, and comprehensive characterization of a novel series of D‐π‐A type malononitrile‐derived chromophores, BTC‐1–BTC‐4. Combining various spectroscopic techniques, nonlinear Z‐scan measurements, and quantum chemical calculations, we revealed the intricate relationship between nonlinear optical properties and the interplay of molecular structure, intramolecular...

artykuł

Appendicitis links to the afterward subsequent psoriatic disease occurrence in Taiwan national health insurance research database: A population‐based cohort study

Chung‐Yuan Hsu, Yu‐Jih Su, Yung‐Heng Lee, Hsian‐Min Chen, więcej

International Journal of Rheumatic Diseases > 27 > 9 > n/a - n/a

Objective To investigate the psoriatic disease risk among patients with previous appendicitis. Methods This study was a nationwide population‐based case–control study about the association between the psoriatic disease risk among patients with a history of appendicitis in Taiwan. The study population consisted of newly diagnosed psoriatic disease with at least two outpatient visits, and the control...

artykuł

A hybrid RSM‐BPNN‐GA approach for optimizing ultrasound‐assisted deep eutectic solvents extraction conditions for Mesona chinensis benth. and investigation of the extraction mechanism

Ping Xie, Ya‐Hui Ye, Chen‐Qing Wang, Jin‐Hai Shen, więcej

Journal of Food Science > 89 > 9 > 5531 - 5546

Abstract Mesona chinensis Benth (MCB) is the source of the most commonly consumed herbal beverage in Southeast Asia and China and is thus an economically important agricultural plant. Therefore, optimal extraction and production procedures have significant commercial value. Currently, in terms of green chemistry, researchers are investigating the use of greener solvents and innovative extraction...

artykuł

Stomatal evolution and plant adaptation to future climate

Guang Chen, Yuan Qin, Jian Wang, Sujuan Li, więcej

Plant, Cell & Environment > 47 > 9 > 3299 - 3315

Global climate change is affecting plant photosynthesis and transpiration processes, as well as increasing weather extremes impacting socio‐political and environmental events and decisions for decades to come. One major research challenge in plant biology and ecology is the interaction of photosynthesis with the environment. Stomata control plant gas exchange and their evolution was a crucial innovation...

artykuł

Germline assessment for alloHSCT candidates over 50 years: A ‘Fast‐Track’ screening in myeloid neoplasms

Sara Torres‐Esquius, Francisco Beas, Tzu Hua Chen‐Liang, Helena Pomares, więcej

British Journal of Haematology > 205 > 2 > 503 - 509

Patients aged 50 or above diagnosed with myeloid neoplasms (MNs) are typically not candidates for germline testing. However, approximately 8% carry pathogenic germline variants. Allogeneic haematopoietic stem cell transplantation (alloHSCT) remains an option for those aged over 50; neglecting germline testing could mask the risk for relative donor cell‐derived MN. We propose a germline‐augmented somatic...

artykuł

Highly efficient palladium‐catalyzed hydroesterification of functionalized alkenes

Chenghui Dai, Yanling Zheng, Haiyan Fu, Jiaqi Xu, więcej

Applied Organometallic Chemistry > 38 > 8 > n/a - n/a

Herein, we introduce a catalytic system consisting of Pd (OAc)₂/Xantphos/Al (OTf)₃, which exhibits excellent reactivity in catalyzing the hydroesterification of a wide range of substrates, including electron‐deficient unsaturated acids/esters, aliphatic alkenes, functionalized styrenes, and phenylacetylenes. The catalytic system featured high reactivity and selectivity, low catalyst loading, wide...

artykuł

Cucurbitacin B attenuates osteoarthritis development by inhibiting NLRP3 inflammasome activation and pyroptosis through activating Nrf2/HO‐1 pathway

Chao Lou, Yuqin Fang, Yifan Mei, Wei Hu, więcej

Phytotherapy Research > 38 > 7 > 3352 - 3369

Osteoarthritis (OA) is a complicated joint disorder characterized by inflammation that causes joint destruction. Cucurbitacin B (CuB) is a naturally occurring triterpenoid compound derived from plants in the Cucurbitaceae family. The aim of this study is to investigate the potential role and mechanisms of CuB in a mouse model of OA. This study identified the key targets and potential pathways of CuB...

artykuł

Manganese Doped Tin Oxide for Stable and Efficient Quantum Dot Light–Emitting Diodes

Wenchen Ma, Zhenwei Ren, Hengfei Shi, Xueqing Xia, więcej

Laser & Photonics Reviews > 18 > 7 > n/a - n/a

As an alternative electron transport material to the chemically unstable ZnO nanoparticles (NPs), SnO₂ NPs exhibit a great potential to construct high‐performance quantum dot light‐emitting diodes (QLEDs). However, only moderate device performance has been obtained for SnO₂‐based QLEDs due to the low electron mobility, unfavorable energy band, and massive defects of SnO₂ NPs. Herein, a strategy of...

artykuł

Guanidinium‐Based Manganese(II) Bromide with High Glass‐Forming Ability for Thermoplastic Curved X‐ray Imaging

Zi‐Lin He, Jun‐Hua Wei, Jian‐Bin Luo, Zhi‐Zhong Zhang, więcej

Laser & Photonics Reviews > 18 > 7 > n/a - n/a

The development of large‐area transparent organic‐inorganic hybrid metal halide (OIMH) scintillation screens is restricted by the anisotropic single‐crystal growth, numerous grain boundaries in polycrystalline wafers, and inhomogeneous dispersion in perovskite‐polymer composite films. The crystal‐glass phase transition of OIMH materials may provide a promising solution for the above significant challenges...

artykuł

Dengue severity in rheumatoid arthritis patients under treatment with disease‐modifying antirheumatic drugs

Hsin‐Hua Chen, Chia Hua Chung, Nicole Huang, Theodore F. Tsai, więcej

International Journal of Rheumatic Diseases > 27 > 6 > n/a - n/a

artykuł

Asthma control associated with anxiety and depression in asthmatic children following post‐acute COVID‐19

Tung‐Ming Chang, Yun Chen, Kuender D. Yang, Jiu‐Yao Wang, więcej

Pediatric Allergy and Immunology > 35 > 6 > n/a - n/a

Background Poor asthma control may adversely affect mental health. Our study investigates the correlation between inadequate asthma control, exhaled nitric oxide (FENO) levels, and anxiety and depression among pediatric asthma patients with COVID‐19. Methods This prospective case–control study enrolled 520 asthmatic children (8–15 years), including 336 patients diagnosed with COVID‐19 after rapid...

artykuł

Palmitic acid induces GSDMD‐mediated pyroptosis in periodontal ligament cells via the NF‐κB pathway

Bing‐Jing Sun, Mei‐Hua Chen, Wei‐Hua Zhang, Bing‐Jiao Zhao, więcej

Oral Diseases > 30 > 4 > 2546 - 2557

Objective Obesity can affect periodontal tissues and exacerbate periodontitis. Pyroptosis, a newly identified type of inflammatory cell death, is involved in the development of periodontal inflammation. The saturated fatty acid palmitic acid (PA) is elevated in obese patients. The effect of PA on pyroptosis in periodontal ligament cells (PDLCs) and its underlying mechanisms remain unknown. Materials...

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Transactions of Nonferrous Metals Society of China (61)
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