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Melatonin and its metabolites including 6-hydroxymelatonin (6(OH)M), N 1 -acetyl-N 2 -formyl-5-methoxykynuramine (AFMK) and 5-methoxytryptamine (5MT) are endogenously produced in human epidermis. This production depends on race, gender and age. The highest melatonin levels are in African-Americans. In each racial group they are highest in young African-Americans [30–50 years old (yo)],...
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