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A nicotinamide adenine dinucleotide (NADH)‐dependent redox‐neutral convergent cascade composed of a recently discovered type II flavin‐containing monooxygenase (FMO−E) and horse liver alcohol dehydrogenase (HLADH) has been established. Two model reaction cascades were analyzed for the synthesis of γ‐butyrolactone and chiral bicyclic lactones. In the former cascade, all substrates were converted into...
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