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Rats were trained to use a single forelimb for a food pellet retrieval task. During baseline testing all rats exhibited >90% use of a preferred limb for the task. Following baseline, rats were subjected to chronic administration (18 day) or acute injection of quinolinic acid (QUIN) or vehicle to the striatum contralateral to the preferred limb. Rats were tested 48 h after insertion of chronic delivery...
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