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The Pro11Leu substitution in the AGXT gene, which causes primary hyperoxaluria type 1, is found with high frequency in some human populations (e.g., 5–20% in Caucasians). It has been suggested that this detrimental mutation could have been positively selected in populations with a meat‐rich diet. In order to test this hypothesis, we investigated the occurrence of Pro11Leu in both herder and agriculturalist...
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