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P. X. Ma and colleagues report the novel functional nanofibrous hollow microspheres (FNF‐HMS) for tissue regeneration on page 350. Peptide decorated FNF‐HMS are shown to directly guide stem cells to form cartilage and bone, respectively, circumventing the use of the expensive and unstable growth factors. FNF‐HMS can therefore serve as an advanced injectable carrier platform for various therapeutic...
Injectable microspheres are attractive stem cell carriers for minimally invasive procedures. For tissue regeneration, the microspheres need to present the critical cues to properly direct stem cell differentiation. In natural extracellular matrix (ECM), growth factors (GFs) and collagen nanofibers provide critical chemical and physical cues. However, there have been no reported technologies that integrate...
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