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In order to further clarify the role of T-type Ca 2+ channels in cell proliferation, we have measured the growth inhibition of human cancer cells by using our potent T-type Ca 2+ channel blockers. As a result, KYS05090, a most potent T-type Ca 2+ channel blocker, was found to be as potent as doxorubicin against some human cancer cells without acute toxicity. Therefore, this...
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