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Chronic kidney disease (CKD) is a disease with decreased, irreversible renal function. Pruritus is the most common skin symptom in patients with CKD, especially in end‐stage renal disease. The underlying molecular and neural mechanism of CKD‐associated pruritus (CKD‐aP) remains obscure. Our data show that the level of allantoin increases in the serum of CKD‐aP and CKD model mice. Allantoin could induce...
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