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Emulsion electrospinning was initially applied to prepare core–sheath structured fibers with a core loading of pDNA or pDNA polyplexes inside a fiber sheath of poly(dl-lactide)–poly(ethylene glycol) (PELA). The inclusion of poly(ethylene imine) (PEI) and poly(ethylene glycol) (PEG) were expected to modulate the release profiles and achieve a balance between cytotoxicity and transfection efficiency...
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