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Renal cell carcinoma (RCC), which arises from the renal tubular epithelial cells, accounts for more than 90% of primary renal tumors in adults. This article reviews the current literature on RCC, including the new histologic subtypes that were included in the latest World Health Organization classification. It also reviews the conventional histopathologic prognostic parameters, potential prognostic...
Caveolae are cell membrane invaginations that were first described in the early 1950s. Since then, researchers have undertaken numerous studies to define their role in normal physiology and disease. The caveolin proteins, particularly caveolin-1, are the major structural and functional components of caveolae, which are involved in a plethora of cellular functions. This review briefly describes the...
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