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We studied the effects of bile stasis in aguinea pig model of pigment gallstone. The common bileducts of guinea pigs were partially ligated, and theguinea pigs killed one or two weeks later. Biliary sludge or stones were examined with the Fouriertransform infrared spectroscopy and the scanningelectromicroscopy. The bile was analyzed for pH, freecalcium, bile acids and bilirubin fractions, and the...
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