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Background
Insulin‐like growth factor 1 (IGF1) is a neurotrophic factor with many actions, including a possible hyperalgesic effect. This study investigated the effects of IGF1 on the overall behavior of diabetic mice and explored the possible mechanisms underlying IGF1‐induced pain.
Methods
Mice were divided into five groups (db/m, db/db, vehicle‐treated db/db, IGF1‐treated db/db, and IGF1 + JB1‐treated...
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