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Yttrium-90 radioembolization is a common treatment for inoperable hepatocellular carcinoma (HCC), where injected Y-90 microspheres give a targeted radiation dose to malignant tissue in the liver. The biodistribution of microspheres are typically determined by SPECT detection of the Y-90 bremsstrahlung x-rays of the beta decay. Clinical interest in Y-90 PET imaging has arisen recently after high resolution...
A combination of breast-dedicated positron emission tomography (PET) with biopsy capability can detect cancer in women with radiodense and/or fibrocystic breasts and simultaneously guide the biopsy of suspicious breast lesions. In this study, Monte Carlo simulation model of the PET components was developed and initial GATE simulation studies were performed to predict the absolute sensitivity, noise...
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