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To examine the independent effects on insulin sensitivity and antioxidative activity of the three most prevalent constituents in Premarin (Wyeth-Ayerst Laboratories, Philadelphia, PA): estrone sulfate (E 1 S), 50%; equilin sulfate (EqS), 25%, and 17α-dihydroequilin sulfate (17α-ES), 15%.Prospective randomized cross-over study.University of Southern California Medical Center.Eight healthy postmenopausal...
To determine the independent biologic effects of 17α-dihydroequilin sulfate.Prospective randomized study.University of Southern California Medical Center.Twenty-one postmenopausal women, mean age 50±2 (±SEM) years, and mean body mass index 27±2.Women were randomized to receive daily oral doses of either 1.25mg of estrone sulfate (E1S), 0.2mg of 17α-dihydroequilin sulfate, or a combination. Three blood...
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