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Cyclin-dependent kinase 2 (cdc2) controls the G2–M checkpoint and, therefore, the entrance of cells into mitosis. It might play a crucial role during tumour progression in colon carcinomas (CCA). Thus, the prognostic value of cdc2 expression and connected markers relevant for proliferation and apoptosis has to be evaluated.Punch biopsies from the tumour centre and the invasion front of 0.6mm diameter...
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