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Type 2 diabetes mellitus (T2DM) is the most common form of diabetes. Compared with the general population, a higher failure rate is seen in T2DM patients. There is also evidence that chronically high levels of plasma glycemia leads to inflammatory effect and a negative influence on bone formation and remodeling, and reduce osseointegration of implants. Recently studies reveal that adiponectin is an...
Since it was firstly reported in 2003, a large number of cases have been published concerning bisphosphonate-related osteonecrosis of the jaw (BRONJ). It has generated great interest in the medical and research communities yet remains an enigma, given its unknown pathogenesis. Many hypotheses concerning the underlying pathophysiology are discussed, including two most popular hypotheses: bone remodeling...
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