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Reporter-gene-based microbial biosensors have high potential for detecting small molecules, including heavy metal ions (HMIs). However, the sensitivity and dynamic range of microbial biosensors are largely limited by the conventional culture environments that rely on the batch-type addition of the small molecules in nutrients and the subsequent genetic induction. In this work, we report a chemostat-like...
Reporter-gene-based microbial biosensors have high potential for detecting small molecules, including heavy metal ions (HMIs), in a sensitive and selective manner by involving low costs. However, the sensitivity and dynamic range of the sensing mechanism are largely limited by the conventional culture environment that relies on the batch-type addition of the small molecules in nutrients and the subsequent...
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