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Deacetoxy/deacetylcephalosporin C synthase (acDAOC/DACS) from Acremonium chrysogenum is a bifunctional enzyme that catalyzes both the ring-expansion of penicillin N to deacetoxycephalosporin C and the hydroxylation of the latter to deacetylcephalosporin C. The R308 residue located in close proximity to the C-terminus of acDAOC/DACS was mutated to the other 19 amino acids. In the resulting mutant pool,...
When Bacillus licheniformis was administered to the white shrimp, Litopenaeusvannamei, although the total bacterial counts in the intestinal tract of the shrimp remained constant, Vibrio numbers significantly decreased (P < 0.05). Haemocyte counts together with phenoloxidase and superoxide dismutase activities of the shrimp were significantly higher (P < 0.05) in treatments than in the control...
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