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AimsWe have demonstrated previously that gross cystic disease fluid protein‐15 (GCDFP‐15) and mammaglobin A (MAM) are of limited utility in triple‐negative breast cancer (TNBC). GATA‐binding protein 3 (GATA‐3) is an emerging breast‐associated immunohistochemical (IHC) marker with limited data in TNBC. Here, we examined GATA‐3 expression in TNBC in comparison with GCDFP‐15 and MAM.
Methods and resultsWe...
Aims: In addition to oestrogen and progesterone receptors, gross cystic disease fluid protein‐15 (GCDFP‐15) and mammaglobin A (MAM) are the most common markers used to identify breast origin by immunohistochemistry. GCDFP‐15 expression has been reported in approximately 60% of breast carcinomas and MAM expression in approximately 80%. Data on their expression in triple‐negative breast cancer (TNBC)...
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