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Optical projection tomography (OPT) is a very important imaging tool for a mesoscopic-scale. It can provide three dimensional (3D) transmission and emission imaging. However, high-resolution OPT is limited in depth of field (DOF) due to a high numerical aperture, which causes a poor performance of OPT in imaging large samples. Moreover, it is difficult to tune the focus plane (FP) to a fixed position...
We have designed a multimodality molecular imaging system for small animals. The aim is to develop a system which can perform functional imaging, structural imaging, and molecular imaging. Our multimodality system contains five imaging modalities which are Bioluminescence Tomography (BLT), Fluorescence Molecular Tomography (FMT), Cerenkov Luminescence Tomography (CLT), X-ray Computed Tomography (CT),...
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