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High‐frequency stimulation of the subthalamic nucleus (STN‐HFS) is highly effective in treating motor symptoms in Parkinson's disease (PD) and medication side effects as well as in improving quality of life. Despite preoperative screening for patients as eligible candidates for this treatment, electrode position may furthermore influence treatment quality. Here, we investigated the relationship between...
Background:The improvement of PD motor symptoms by DBS of the STN depends on exact targeting.
Methods:A combination of MRI and multitrajectory microrecordings was used for localization of the STN in a group of 228 consecutive PD patients.
Results:In 1% of our cases, the STN was consistently shifted in the anterior (3.3 ± 0.8mm) and medial (3.0 ± 0.9mm) direction within the target plane, compared...
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