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The single-dose effect of formoterol racemate and enantiomers on bronchodilatation up to 24h was determined. Forty-six reversible asthmatic patients were randomised to this double blind, crossover study. Formoterol was inhaled by nebulizer (HaloLite ® ); 4.5 and 36μg of the racemate (rac-formoterol), 2.25 and 18μg of (R;R)-formoterol, 18μg of (S;S)-formoterol, or placebo. Airway and systemic...
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