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Aflatoxin B1 (AFB1) and fumonisin B1 (FB1) are mycotoxins commonly coexisted in cereal-based ingredients or foods, and their co-apoptotic activity in HepG2 cells was studied to further the understanding of their combinative toxicity. The values of IC50, based on sulforhodamine B (SRB) colorimetric assay, were 9.5μM and 481.7μM for AFB1 and FB1, respectively, showing AFB1 is more toxic to HepG2 cells...
Aflatoxin B1 (AFB1) and sterigmatocystin (ST) are two hepatocarcinogenic mycotoxins that are commonly coexisted in cereal grains, and their co-proapoptotic activity in HepG2 cells was studied. The values of IC50, which is the dosage of mycotoxin resulting in a 50% cell growth inhibition measured by a sulforhodamine B (SRB) colorimetric assay, were 16.9 μM and 7.3 μM for AFB1 and ST, respectively....
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