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Epithelial to Mesenchymal Transition
The cover image shows that the malignant cells generated by the epithelial‐mesenchymal transition (EMT) are breaking away from the benign ones and spreading elsewhere. In article number 2106498, using single‐particle tracking of β1‐integrins labelled with fluorescent quantum dots, Yan Wei, Peng‐Ye Wang, Hui Li, and co‐workers discover a significantly enhanced diffusion...
Cell morphology and migration depend critically on the adhesions on the extracellular matrix (ECM), determined by the transmembrane protein integrins. The epithelial to mesenchymal transition (EMT) is a prominent transformation process in which adherent cells acquire a mesenchymal phenotype and a promoted migration. EMT plays important roles in embryonic development and cancer metastasis, and its...
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