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Phosphatidylcholine(PC)–cholesterol (0–30 mol%) unilamellar vesicles of several sizes (20–600 nm) were prepared in buffer (pH 7.4) solutions by sonication or extrusion methods. The vesicle size was measured by a dynamic light-scattering method. Absorption spectra of chlorpromazine (CPZ) and triflupromazine (TFZ) in the presence of these vesicles showed a bathochromic shift according to the increase...
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