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Eine ungewöhnliche chimäre Terpensynthase wurde aus Emericella variecolor erhalten. I. Abe et al. zeigen in der Zuschrift auf S. 1690 ff., dass diese Synthase Kondensation und Cyclisierung durch ihre Prenyltransferase‐ (PT; grün/gelb) bzw. ihre Terpencyclase‐Domäne (TC; türkis) katalysiert. Ihre Expression in Aspergillus oryzae führte zu einem neuartigen C20‐Diterpen und der Austausch der PT‐Domäne...
Di‐ and sesterterpene synthases produce C20 and C25 isoprenoid scaffolds from geranylgeranyl pyrophosphate (GGPP) and geranylfarnesyl pyrophosphate (GFPP), respectively. By genome mining of the fungus Emericella variecolor, we identified a multitasking chimeric terpene synthase, EvVS, which has terpene cyclase (TC) and prenyltransferase (PT) domains. Heterologous gene expression in Aspergillus oryzae...
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