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Niemann–Pick disease type C1 (NPC1) is a lysosomal lipid storage disease caused by NPC1 gene mutation. Our previous study found that, compared with wild‐type (Npc1+/+) mice, the renal volume and weight of Npc1 gene mutant (Npc1−/−) mice were significantly reduced. We speculate that Npc1 gene mutations may affect the basic structure of the kidneys of Npc1−/− mice, and thus affect their function. Therefore,...
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