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Patients with severe asthma are less responsive to corticosteroid therapy and show increased airway remodeling. The mesenchymal progenitors, fibrocytes, may be involved in the remodeling of asthmatic airways. We propose that fibrocytes in severe asthma are different from those in nonsevere asthma.To examine the survival, myofibroblastic differentiation, and C-C chemokine receptor 7 (CCR7) expression...
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