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A mathematical model of mean airway pressure (Pmean) has been derived which is based upon positive end-expiratory pressure (Ppeep) and I:E ratio (I:E). Plateau pressure (PPL) is also utilized: $$ P_{\rm mean}/P_{\rm PL} = [(I{:}E) + {\bf R}]/[(I{:}E) + 1] $$ where R is defined as: R = Ppeep/PPL. Based upon this model, it can be shown that (1) increasing I:E ratio will increase Pmean/PPL in...
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