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Cardiovascular diseases and dysfunctions of the reproductive system are common complications of type 2 diabetes (T2D), and, therefore, development of new approaches for the alleviation of these pathologies is highly important. Bromocriptine (BC), an agonist of type 2 dopamine receptors, recently became widely used for the treatment of type 2 diabetes; this drug both restores energy metabolism and...
In type 1 diabetes mellitus (DM), changes occurring in the adenylyl cyclase signaling system (ACSS) are one of the key causes of complications of the disease. Since type 1 DM has been most often diagnosed in childhood and adolescence, the study of changes in ACSS in the early development of the disease is a genuine problem. For this, we developed a prolonged model of type 1 DM, which was induced by...
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