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Purpose: Although the potential benefits of radiation therapy and chemotherapy in the management of completely resected AJCC N1 non-small cell lung cancer are unknown, the majority of studies have failed to demonstrate a survival benefit with any neoadjuvant or adjuvant therapy. While it is possible that radiation therapy and chemotherapy are ineffective adjunctive therapies in this disease, it is...
Purpose/Objective: Previous studies of patients with surgically resected nonsmall cell lung cancer and chest wall invasion have shown conflicting results with respect to prognosis. Whether high risk subsets of the T3N0M0 population exist with respect to local, regional, and distant control as well as overall survival has been difficult to ascertain due to small numbers of patients in most reported...
Purpose: In some surgical practices the procedure of mediastinal nodal dissection is considered unnecessary in the treatment of non-small cell lung cancer if pathological frozen sections reveal lack of involvement of N1 lymph nodes. This philosophy is based on the paradigm that nodal spread in non-small cell lung cancer follows a contiguous pattern of spread from N1 lymph node stations to N2 lymph...
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