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Wang, Y. F., Y. K. Mao, J. E. T. Fox-threlkeld, T. J. McDonald and E. E. Daniel. Colocalization of inhibitory mediators, NO, VIP and Galanin, in canine enteric nerves. Peptides 19(1), 99-112, 1998.-The colocalization of three putative inhibitory mediators of enteric nerves, vasoactive intestinal peptide (VIP), galanin (GAL) and nitric oxide synthase (nNOS), was examined in the myenteric plexus of...
Objective: We hypothesize that during severe normothermic hemorrhagic shock (HS), induction of profound hypothermic circulatory arrest (PHCA) of 60 min to allow repair of otherwise lethal injuries in a bloodless field, can be survived without brain damage. In previous dog studies, normothermic HS with mean arterial pressure (MAP) of 40 mm Hg for 30 min, followed by PHCA of 2 h at brain (tympanic...
Amphiphilic acrylamide monomer containing a cholesterol moiety as a hydrophobic group and a phosphatidylcholine analogue as a hydrophilic group was synthesized in high yield. Radical polymerization was carried out in the presence of α,α'-azobisisobutyronitrile (AIBN) as initiator. The obtained monomer and homopolymer were characterized by H-NMR, 1 -NMR, IR and melting point, respectively....
The binding of [ 3 H] substance P (SP) was localized and characterized in canine small intestine. The highest density of [ 3 H] SP binding occurred in the fraction enriched in circular muscle membranes (B max 148 ± 14 fmol/mg; K d 0.81 ± 0.01 nM). In the kinetics studies binding was reversible, yielding a similar K d value. NK 1 agonists...
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