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Myocardial infarction (MI) is a leading cause of morbidity and mortality worldwide. As mitochondrial dysfunction critically contributes to the pathogenesis of MI, intensive research is focused on the development of therapeutic strategies targeting mitochondrial homeostasis. Mitochondria possess a quality control system which maintains and restores their structure and function by regulating mitochondrial...
Aim
This study determines whether the activation of olfactory calcium‐sensing receptor initiates a sympathetic activation‐dependent neurovascular reflex subsequently contributing to renal hemodynamic depression.
Methods
Immunohistochemistry and nose‐loading calcium‐sensitive dye were used to explore the location and function of calcium‐sensing receptor on the olfactory sensory neuron. The renal...
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