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Micromolar concentrations of arachidonic acid cause in Ca 2+ loaded heart mitochondria matrix swelling and Ca 2+ release. These effects appear to be unrelated to the classical membrane permeability transition (MPT), as they are CsA insensitive, membrane potential independent and can also be activated by Sr 2+ . Atractyloside potentiated and ATP inhibited the arachidonic acid...
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