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Characterization of tissue elasticity (stiffness) and viscosity has important medical applications because these properties are closely related to pathological changes. Quantitative measurement is more suitable than qualitative measurement (i.e., mapping with a relative scale) of tissue viscoelasticity for diagnosis of diffuse diseases where abnormality is not confined to a local region and there...
Vibro-acoustography (VA) displays the vibroacoustic response of the object (tissue) induced by two intersecting ultrasound beams of different frequencies. VA image of a given object may vary depending on boundary conditions. Such variations are attributed to the reverberation of the sound emanating from the object in the acoustic environment of the experiment. This effect can be explained in terms...
We propose a method using broadband tone burst excitation pulses with non-uniform sampling for Shearwave Dispersion Ultrasound Vibrometry (SDUV). The method allows long excitation pulses with a high PRF of detection pulses to induce a strong tissue motion and obtain strong detection signal. The method also simultaneously estimates all harmonics of tissue motion induced by the broadband excitation...
Measurement of liver elasticity (i.e., stiffness) can be used as a noninvasive alternative to liver biopsy to stage liver fibrosis, a condition afflicting hundreds of millions of patients worldwide. Quantitative measurement of stiffness (in unit of Pascal) is required because liver fibrosis is a diffuse disease where abnormality is not confined to a local region and there is no normal background tissue...
A method has been developed to quantitatively analyze sinoatrial nodes (SAN) using Doppler tissue images (DTI). Doppler tissue images of SAN are acquired using an intracardiac catheter via the superior vena cava in an in vivo experiment. A sequence of DTI images of a SAN is obtained, and a complete cycle of the SAN excitation is observed. The tissue acceleration of the SAN is extracted and quantitatively...
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